There were 78 men and 42 females as we grow older of (4.2±0.8) many years and scar section of (100.3±0.7) cm(2). PDL along with UFCL had been used for the 1st time. The treatment period of PDL had been a month and also the therapy interval of UFCL was 3 months. The sum total therapy pattern was half a year, with 2 PDL remedies alone and two mixed treatments. Prior to the first combined treatment and 6 months after two blended treatments, the curative result ended up being assessed making use of Patient and Observer Scar Assessment Scale (POSAS) by health practitioners and fcan alleviate symptoms and increase the quality of pediatric patients’ life, and it is worthwhile becoming popularized and applied in clinic.Objective to research the expressions and effects of autophagy-related genetics in bleomycin-induced epidermis fibrosis of mice. Methods (1) completely 72 male BALB/c mice elderly 6 months were divided into blank control team, quick phosphate buffer option (PBS) team, and bleomycin team according towards the random number table, with 24 mice in each group. Mice in blank control team received no therapy, and 100 μL of PBS and bleomycin (1 mg/mL) had been read more correspondingly injected subcutaneously in the back skin of mice in simple PBS and bleomycin team, once a day for 28 days. On shot day (ID) 7, 14, 21, and 28, 6 mice in each group were gathered to see skin change on the straight back of mice with naked eyes. Following the observation, the mice were sacrificed and skin tissue in the back had been taken. Body muscle of mice on ID 28 was collected to measure the depth of skin tissue by routine hematoxylin-eosin staining and observe skin structure morphology by Masson staining. Skin structure on ID 7, 14, 21, and 28 was taken to dete (t=0.82, 0.45, 0.50, 0.79, 0.51, 0.50, P less then 0.01). On ID 28, the protein expressions of p62, LC3 Ⅱ, and Beclin-1 in the epidermis structure of mice in bleomycin team had been somewhat lower than those who work in empty control team and easy PBS group (t=0.77, 0.54, 0.52, 0.50, 0.51, 0.50, P less then 0.05). (7) After culture for 72 h, the phrase of LC3 Ⅱ in Fbs of bleomycin group was substantially reduced than that of blank control group and simple PBS group, respectively. Conclusions in the act of bleomycin revitalizing skin fibrosis, autophagy-related genes increase firstly and then reduce. Once the autophagy procedure is triggered, its anticipated to reverse the process of skin fibrosis.Objective to research the medical effect of Zhang’s very tension-relieving suture applied in high-tension injury closing. Techniques From January to August 2019, 19 eligible patients with scar or black hairy nevus were treated with Zhang’s extremely tension-relieving suture for outpatient operation in the Department of vinyl and Reconstructive Surgery of Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University class of drug. The patients were consists of 6 guys and 13 females, aged 10-68 many years, with 8 keloids, 3 hypertrophic scars, 5 atrophic scars, and 3 black colored hairy nevus. The procedure websites included reduced jaw in 2 cases, neck in 3 instances, upper body in 4 instances, abdomen in 2 instances, and limbs in 8 situations. How big scars and black hairy nevus before surgery ranged from 1.4 cm×1.1 cm to 10.0 cm×4.0 cm. All of the lesions underwent excision alone with both sides of this incision undermined for one to two cm, and also the wound size ranged from 2.6 cm×2.6 cm to 12.6 cm×6.8 cm. Zhang’s very tension-relieplied in high-tension wound.Keloid is a disease this is certainly hard to heal and it has a high recurrence price. In the past, research on keloid centered on keloid cells themselves therefore the therapeutic method limited by neighborhood treatment, whereas the part of systemic elements in the act of occurrence and improvement disease was frequently ignored. On the basis of the literary works reports and medical proof, we suggest that the pro-inflammatory constitution of keloid clients can act as a systemic element to interact with neighborhood facets such as epidermis lesion, and so causes the initiation and development of keloid. The classical concept about close relationship between visceral malfunctions and skin conditions described in traditional Chinese medicine has provided promoting evidence. Consequently, we declare that systemic anti inflammatory treatment ought to be contained in the design of future keloid therapeutic techniques and become confirmed because of the medical tests. Also, the healing methods of standard Chinese medicine including anti-dampness, detoxing and heating removing can also be used as a part of systemic treatment of keloids.Coronavirus disease 2019 (COVID-19) is actually a global public health emergency threatening men and women’s everyday lives all over the world. Although the acute breathing distress syndrome (ARDS) caused by COVID-19 is similar to the ARDS caused by other diseases when it comes to pathophysiological basis and medical manifestations, they are also various in a lot of aspects, which cause various medical therapies. Therefore, understanding the distinctions and similarities of ARDS induced by COVID-19 and other conditions presently are the foundation for physicians to make decisions to treat COVID-19 induced ARDS.Since the outbreak and spread of coronavirus infection 2019 (COVID-19) pandemic, Chinese government has brought numerous steps to protect people’s wellness.